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Lifting Heavy or Light Weights Give You Different Results — Here’s How to Know Which Ones to Use

Resistance training is crucial for building muscle mass, but you’ll get very different results if you lift light or heavy weights.

Resistance and Strength training is beneficial not just for aesthetic results but also for your overall health and longevity. One main issue is whether you should lift heavy weights with a low amount of reps, or light weights with more reps.

Example: Low weight training might mean doing three sets of 40 bicep curls with a 2kg dumbbell, whereas high-weight training might be three sets of five bicep curls with 14kg dumbbells. 

Lifting light may help you build a lean physique

Two popular workout classes of the moment are spinning and barre, both of which often incorporate work with light weights.

Low weight and high repetition training is fantastic for those looking for defined and lean muscles without bulk.

Generally speaking, heavy weight training is geared toward adding muscle mass, whereas high repetition training creates longer-looking muscle as less power is needed and the entire length of the muscle is used to create each contraction.

With high repetition training it creates a lactic acid burn on the muscle groups of focus creating a hormone reaction that occurs over the few days post-workout.

Ultimately, it is working out to the point that your muscles are beginning to burn and shake, which is commonly what happens with high repetition and low weight training. Sticking to low weights but working at a high rep rate so your muscles end up shaking could lead to burning more calories afterwards, but that’s not the only positive. Light weights cause fewer injuries than heavy ones

Working with light weights allows you to perform movements through your full range of motion properly and precisely . Plus, the risk of injury is much lower.

As we age, we can develop joint problems and this can also be exasperated by the wrong kind of training. Using lighter weights and incorporating longer reps will only empower the body, not hit it abruptly.

Lifting heavy will help you build strength

If you want to build bulging muscles, however, lifting heavy is the way to go, which means choosing weights so heavy you can’t do very many reps at a time.

Higher loads and lower reps produce strength gains. However, this doesn’t mean that by lifting heavy you’ll immediately start resembling a body-builder, and you’ll only build muscle if you’re in a calorie surplus — ie. consuming more energy than you’re burning. 

If your goal is simply to improve your body composition, performing 3-4 sets of 8-12 reps per exercise — you need to choose a weight that allows you to do that, but also feel pushed.

Aesthetic changes are, broadly speaking, about reducing body fat in relation to lean tissue, so aim to produce a hypertrophy response whilst manipulating calories (surplus to gain muscle, deficit to lose fat). For this hypertrophy response, you need to be lifting heavy enough weights. 

What does the science say?

In 2012, a study by McMaster University was undertaken to compare the training effects of light weights to heavy weights in young men.

The researchers tested the effects of performing leg extensions with either light (30% of 1 rep max) or heavy (80% of 1 rep max) weights over a 10 week period.

Interestingly, the researchers found that both heavy and light loads increased muscle size equally.

The key is that both loads were lifted to exhaustion. That means the 80% group was lifting a weight that made them fatigue after about 10 repetitions, while the 30% group was lifting weights that tired them out after about 35 repetitions.

What this tells us is that, as long as each set is taken to muscular fatigue, the load lifted isn’t as important as the maximal effort applied for building muscle. This is because all muscle fibers will be recruited as a load is repeatedly lifted to failure.

While the researchers found both techniques were equally efficient at building muscle, they also discovered that for building strength, the 80% load produced superior results.

For building strength, it is better to lift heavier weights because the heavier loads train your nervous system to be able to recruit more of your muscle cells to produce more force more quickly, something that a light load will not duplicate.

So in general, one would be most likely to realize the best benefits of muscle and strength-building by repeatedly lifting heavier loads (80%+) to the point of near-fatigue (6-10 reps, but leave a little something in the tank) over time, as this could be done with a much lesser likelihood of inducing burnout.

There are pros and cons of both

There are undeniably pros and cons to both ways of resistance training.

Training with low weight and a high number of reps generally means a shorter recovery period between workouts, along with shorter rest periods between sets. The number of calories burned is likely to be higher and there’s less pressure on joints.

On the flip side, training this way is likely to take longer to build bigger muscle and you’re not likely to improve your strength massively. Whereas when lifting a higher weight with lower reps, you’ll definitely see your strength improve, along with bone density and a greater fat loss. The cons of this type of training are that you’ll need a longer recovery period for the muscle group in training, your workout is likely to be longer, and you’re placing joints under a lot of stress.

How to get results from your weight training

Which training method you choose really depends on what you’re hoping to achieve, what works for you, and just what you enjoy. What’s key, however, is that you create what’s known as progressive overload — this means either increasing weight volume or number of reps over time, intensity or frequency or exercising techniques.

However, progression will not always be linear — there is a point at which you will not be able to perform more reps or add more weight.

Both heavy and light weights will help you build muscle. Ultimately, training with either light or heavy weights is going to be beneficial, or you can mix it up by incorporating both into your regime. Just make sure you work hard enough that your muscles start to fatigue .

The most important thing is the understanding that resistance training is the key to pretty much every training goal.

Reference and excerpts from :

https://www.insider.com/how-lifting-heavy-or-light-weights-affects-the-body-in-different-ways-2019-3

~Praveen Jada

*Do read the Disclaimer

How do you Leave an Impact in This World

In our lifespan we need to determine at some point to make a difference in this world. We need to ponder how to leave this world a better place to live then the one you found when were born.

Not everyone can create a positive impact that could be felt by a very large population. However, anything we do necessarily need not have a huge impact. It is enough in our entire life, even if we touched few lives and contributed to their well being .

For this we need to commit to consistently work on ourselves in alignment with our values. We work with passion and zeal only when we are working on something that matches with our ideals and values. When we are working in alignment with our values, we get a sense of satisfaction and fulfilment as there is a meaning to the work we do. In this state, we simply love the work we do.

While pursuing our passion, it is necessary to define our ‘Purpose’ or ‘Why’. We need to question ourselves and find answers for what’s the purpose behind this work, why am i doing this, what’s the objective and so on. Now, here comes the main part, the purpose ultimately need to be connected to service and contribution.

Significance comes only when our work serves others and adds value to other’s lives. Our work becomes impactful when our contribution is making a positive difference in other’s lives. In the process of committing ourselves to our passion with a purpose, we can leave an indelible mark in our people’s lives through our service. This is how we can have a legacy and create a long lasting impact.

Creating a legacy for ourselves is like planting a seed and nurturing it to be a healthy tree. Though not having an expectation to enjoy the fruits of the tree for oneself.

It is not important and necessary for every one of us to do extraordinary feats to reach prominence because not everyone of is extraordinarily gifted. However, it should be possible for all of us to do choose one ordinary thing we love and work on it extraordinarily to make a difference.

~Praveen Jada

*Do read the Disclaimer

Foods to Break Your IF and What to Eat During Feeding Window

Refer Basics of Intermittent Fasting or Time Restricted Feeding (TEF) to understand the the basics before reading this topic.

Here are some of the recommended and supplements while doing Time restricted feeding (TEF) or IF.

Remember that doing fasting does not give you the license to binge eat or eat mindlessly. What we eat during the feeding window matters and the benefits of fasting would be enhanced by having a nutrient rich whole food. Make sure that you get all the nutrients and required calorie intake while eating.

It has been proven many times that what we eat in terms of quality and quantity is more important than when and how many times we eat.

Protein

Have a diet rich in quality protein. we can get high quality protein mainly from animal and dairy sources. For vegetarians, there are options available to compensate protein needs from seeds, nuts, lentils. However, vegetarian proteins will come with carbohydrates and fats in them. So one needs to keep a tab on the total food or calories while eating these kind of foods. For people who do not have such food restrictions, you can mix both veg and non-veg protein sources to get the best of both food groups. Also veg protein foods like lentils and beans also contain complex carbohydrates and soluble fiber which is good for gut and sustained energy. Nuts like almonds and peanuts are high in protein but they are high in healthy fats.

Examples of protein: Eggs, fish, chicken, red meat, paneer, plain Greek yogurt, curd, whole milk.

Complex Carbohydrates

Eat a variety of vegetables and fruits of different colors daily. They are good source of fiber, phytonutrients, anti-oxidants, minerals and vitamins. Whole grains, lentils, beans, peas, millets are high in carbohydrates and fiber. They come with good dose of protein as well.

Examples of complex carbs: Sweet potatoes, beans and lentils, oats (steel-cut, rolled, old-fashioned), corn, barley, buckwheat, quinoa, whole or sprouted grains and whole-grain rice (brown, black, wild).

Healthy Fats

These fats will come from a variety of sources like nuts, nut butters, and oils, sticking with anti-inflammatory oils like extra-virgin olive and avocado. Unless you’re following a specific diet, healthy fats shouldn’t exceed more than 30-35 percent of your daily calories.

Examples of healthy fats: Oils (extra-virgin olive, walnut, avocado), unprocessed cheese like cheddar and mozzarella, egg yolks, seeds (chia, flax, hemp, pumpkin, sesame), nuts (cashew, walnut, almond, peanut, brazil, pecan, pistachio), natural nut butters, unprocessed coconut oil, any cold pressed oils.

What Foods Should You Avoid When Practicing Intermittent Fasting?

These foods will keep you from losing weight efficiently when you’re practicing intermittent fasting. They’re short on nutrients and harder on the digestive tract than their fresh, wholesome counterparts.

  • Sugary drinks and foods
  • Alcohol
  • Fried foods
  • Highly processed foods
  • Refined carbohydrates like maida
  • Refined oils
  • Excessive caffeine

Takeaway

Of course, you may follow any diet as per your convenience but if you do not design a well balanced diet you’ll miss out on fasting benefits. Eating nutrient dense foods will help you maximize your intermittent fasting efforts as well as increase your overall health, reset your metabolism, and help you lose weight faster.

~Praveen Jada

*Do read the Disclaimer

As A Parent, Be a Role Model and Lead By Example

As a parent , be a role model, be a leader, act like a CEO of your family, be a hero for your child to follow your footsteps. In this day and age, I believe that only way to raise our kids as responsible and sensible citizens is to show practically how to be like one.

For this to happen there is one aspect in our life that is completely in our control and that is our health and fitness. The positive effects of effort we put into being physically fit and leading a healthy lifestyle percolates down to other areas of life.

In this fast paced stressful life, eating has become an addiction. We resort to food for any emotional reaction whether we are sad or angry or joyful or failed at something or achieved something. We need to develop healthy eating habits for our child to be conscious about the food they consume. Childhood Eating Habits typically Continue Into Adulthood. We are what we eat, so our eating habits may make or break our overall wellbeing in future.

Physical activities, playing sports and regularly exercising makes you a fit and healthy person. It builds discipline and self-confidence. It makes us stand out among others. It natures sportsmanship. Follow a consistent fitness routine to inspire our children to go be physically involved in sports and games instead of spending time in house playing video games or watching TV. Playing outdoor games would instill competitive spirit and let them experience the importance of teamwork in early age. 

According to latest researches lack of sleep is more dangerous than not exercising or having unhealthy diet. Lack of sleep is major reason behind many mental and metabolic ailments. We need to maintain a healthy sleep routine and then expect our kids to have a good night’s rest instead if spending time with mobiles or TV.

Do not smoke, do not consume alcohol and abuse medicines/drugs. Never fall into peer pressure yourself first and then we can expect our children to have self-control when they are pressured into such situations.

Develop an excellent work ethic and respect for time. Be punctual in starting to office on time and reaching home on time. Never be late to any appointment whether at work or at home. Children watch us managing tasks with efficiency which inspires them be diligent in school and later in life.

Nothing worth comes easy. If great things were easy to achieve anyone could have had all desirable things in life. We need to develop the persistence to  delayed gratification. We need to be able to sacrifice good things today to experience great things later. We need to demonstrate this to our children through our choices and well planned decisions. 

Handle stressful situations with stability. Anybody can smile, care, share and be loving when everything is hunky dory around them. It takes a great deal of patience and restraint to keep a smile on our face and be a pillar of strength for others in times of difficulties. Our show of strength and equilibrium during tough times would become stories to our kids which teach them to keep moving forward when life gets tough.

Now a days we are bombarded with so much of information through various media. To be wealthy, be successful, be beautiful or handsome, wear something to look cool, to apply something on your body to get something. We have so many distractions around us to influence our way of living, our judgement, how we feel about ourselves, our lifestyle. Anybody and anything can take advantage of our insecurities. As a parent we need to have high self-esteem and be conscious to make independent decisions.

Comparisons could lead to unhappiness and dissatisfaction in life. Make sure that our kids are appreciated for what they are and demonstrate that our self-worth comes from within.

Teach our kids that there is no overnight success and talent seldom beats disciplined hard work. Even a small activities like folding the blanket after waking up or brushing the teeth at night if done consistently without missing builds self-confidence. When we could do boring insignificant things daily with discipline, it develops a mindset of commitment. The same things that are easy to do are also the ones that are easy not to do. Consistent growth and progress is more important than the end goal or success.

Developing good habits in early stages of life is very important as they continue lifelong. The values our kids embrace at early stages would create their identity and defines their self-image. For example, being honest and saying truth in important irrespective of the end result. Teach them, show them, lead them by being honest, having integrity in what you say or do, showing accountability and taking full responsibility of the decisions you take, showing up and keep your promises you made to yourself and others.

~Praveen Jada

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References:

Some excerpts taken from inspirational talks of motivational speakers

Ketosis and Ketogenic Diet: Benefits

The ketogenic diet is a high-fat, adequate-proteinlow-carbohydrate diet that in medicine is used primarily to treat difficult-to-control (refractory) epilepsy in children. The diet forces the body to burn fats rather than carbohydrates.

Normally, the carbohydrates contained in food are converted into glucose, which is then transported around the body and is particularly important in fueling brain function. However, if there is little carbohydrate in the diet, the liver converts fat into fatty acids and ketone bodies. The ketone bodies pass into the brain and replace glucose as an energy source. An elevated level of ketone bodies in the blood, a state known as ketosis. When this happens, your body becomes incredibly efficient at burning fat for energy. It also turns fat into ketones in the liver, which can supply energy for the brain .

Ketogenic diets can cause massive reductions in blood sugar and insulin levels. This, along with the increased ketones, has numerous health benefits.

  • Low-carb diets lead to more short-term weight loss than low-fat diets. However, low-carb diets seem to lose their advantage in the long term as it may not be sustainable for majority of people.
  • A large percentage of the fat lost on low-carb diets tends to be harmful visceral(belly) fat that is known to cause serious metabolic problems.
  • Low-carb diets are very effective at lowering blood triglycerides, increasing HDL cholesterol, reducing in blood pressure, possibly even reversing type 2 diabetes.
  • Low-carb and keto diets have proven beneficial in treating epilepsy in children and are being studied for their therapeutic effects on other brain conditions in general population.

 References:

https://www.dietdoctor.com/low-carb/ketosis

https://www.healthline.com/nutrition/10-benefits-of-low-carb-ketogenic-diets#TOC_TITLE_HDR_12

https://www.webmd.com/diabetes/type-1-diabetes-guide/what-is-ketosis

~Praveen Jada

*Do read the Disclaimer

Protein Supplements: Whey Protein

Protein is an essential nutrient for life, responsible for numerous functions, like supporting the building of tissue, cells and muscle. Proteins are made from a collection of up to 20 amino acids.

Proteins vary in their absorption rate within the body, based on their biological value (BV). BV is not a % but a value that takes egg as a constant at 100. It has been proven in many studies that whey protein has a higher BV than egg. So whey protein is a high quality protein that has a high absorption rate in our body.

Milk contains two proteins, whey and casein. In terms of macronutrients, whole milk is comprised of 88% water, 5% carbohydrates, 4% fat and 3% protein. Most of the whey protein powder on the market is a byproduct derived from cheese making.

Whey is a fast-digesting, complete protein that naturally contains all of the essential amino acids (EAAs) that your body cannot make on its own and have been shown to support muscle recovery. When taken over time, in combination with regular resistance exercise, whey can help support muscle building.

There the three types of Whey protein supplements:

  1. Whey protein concentrate (WPC) – About 70–80% protein; contains some lactose (milk sugar) and fat. Cost effective.
  2. Whey protein isolate (WPI) – 90% protein, or higher; contains less lactose and fat. Good for lactose intolerant people. Costlier than WPC.
  3. Whey protein hydrolysate (WPH) – Hydrolyzed whey, this type has been pre-digested so that it gets absorbed faster. Price higher than WPI.

Whey protein supplement is best way to compensate our protein requirements in a day. Since majority of us may not have the resources, quality foods, preparation time every day and every part of the day, having a whey protein supplement would help us meet our protein needs.

It is always recommended to get the nutrition from natural foods. When we fall short of nutrition due to some reason, supplements help us reach our daily diet goals.

Concerns about protein causing kidney damage and contributing to osteoporosis are unwarranted and unproven. People with predisposed kidney and liver health need to take special care.

References:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905294/

10 Evidence-Based Health Benefits of Whey Protein – Healthline

~Praveen Jada

*Do read the Disclaimer

Inflammatory Foods and Habits

Some of the pro-inflammatory foods and habits that could cause stress on our immune system are listed below. Indulging in these foods or habits could negatively alter our immune system functioning and results in inflammation in various systems of our body.

Subsequently this kind of inflammation which is low grade and chronic which is caused by our lifestyle choices results in metabolic disorders like obesity, diabetes, high BP, elevated triglycerides, heart ailments, brain disorders, autoimmune diseases etc.,

Inflammatory Foods:

  1. Sugar and foods rich in sugar like desserts, pastries, chocolate bars, soft drinks, fruit juices, biscuits, sweets, many breakfast cereals etc. Just be aware that other forms of sugar like coconut sugar, palm sugar, brown sugar, jaggery etc., may be relatively better than sugar as they have some trace minerals. However, the negative impact that they all have in our bodies is more or less the same. So having sweets and sugary foods in moderation is important.
  2. Preservatives, flavoring agents, artificial sweeteners, coloring substances, MSG added to packaged foods. They are found not only inflammatory but also carcinogenic as per some researches.
  3. Refined oils and reusing oil multiple times for frying food.
  4. Trans fats – Found in deep fried food like French fries, chicken fries etc., ultra-processed packaged food products, frozen foods.
  5. Refined carbohydrates like refined flour(a.k.a. refined wheat flour or all-purpose flour or Maida), many breakfast cereals which are sprayed with sugar syrup.

Inflammatory Habits:

  1. Lack of exercise and being sedentary
  2. Irregular eating habits and frequent snacking between meals
  3. Drinking Alcohol
  4. Smoking
  5. Insufficient sleep
  6. Stress and anxiety

~Praveen Jada

*Do read the Disclaimer

What is Metabolic Syndrome

Metabolic Syndrome is a cluster of conditions that increase the risk of heart disease, stroke and diabetes.

These conditions include increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels. Having just one of these conditions doesn’t mean you have metabolic syndrome. But it does mean you have a greater risk of serious disease.

Metabolic Risk Factors that could result in Metabolic Syndrome

  • A large waistline or High Visceral Fat.
  • A high triglyceride level
  • A low HDL cholesterol
  • High blood pressure
  • High fasting blood sugar
  • Insulin Resistance (Pre Diabetes)

Other conditions that may play a role in metabolic syndrome:

  • A fatty liver (excess triglycerides and other fats in the liver)
  • Polycystic ovarian syndrome (a tendency to develop cysts on the ovaries)
  • Gallstones
  • Breathing problems during sleep (such as sleep apnea)

How to prevent:

  • Having a good lifestyle
  • Keeping body weight in control and having a healthy weight
  • Eating nutritious whole food
  • Regular exercise
  • Resting or sleeping well
  • Managing mental stress
  • No Smoking
  • Reduce drinking alcohol

References:

https://www.nhlbi.nih.gov/health-topics/metabolic-syndrome

https://www.webmd.com/heart/metabolic-syndrome/metabolic-syndrome-what-is-it#1

https://www.healthline.com/health/metabolic-syndrome

~Praveen Jada

*Do read the Disclaimer

Vitamin D3 Facts, Foods Rich in Vitamin D3, Supplementation

  • Researches say that close to 70% of world could be facing an epidemic of D Vitamin deficiency.
  • Vitamin D has a huge impact on the health and function of your cells. It reduces cellular growth (which promotes cancer) and improves cell differentiation (which puts cells into an anti-cancer state).
  • That makes vitamin D one of the most potent cancer inhibitors — and explains why vitamin D deficiency has been linked to colon, prostate, breast, and ovarian cancer.
  • What’s even more fascinating is how vitamin D regulates and controls genes. It acts on a cellular docking station, called a receptor, that then sends messages to our genes.
  • That’s how vitamin D controls so many different functions – from preventing cancer, reducing inflammation, boosting mood, easing muscle aches and fibromyalgia, and building bones.
  • These are just a few examples of the power of vitamin D. When we don’t get enough it impacts every area of our biology because it affects the way our cells and genes function.

How to get Vitamin D

  • Natural Foods: Eggs, Fish like Salmon and Cod, Fish oil, Some types of Mushrooms, Un processed Cheese.
  • Supplementation: cholecalciferol-D3 daily supplements. Dosage will be based on individual’s current Vitamin D levels.
  • Sunlight: 20 to 30 minutes in mid-day sunlight with majority of the body (mainly bare back) directly exposed to sunlight. People with darker skin may need close to an hour under sun.

Supplementation

Many researches prove that vitamin D supplementation is beneficial for

  • Bone disorders and calcium metabolism issues in body
  • Bone loss in people taking drugs called corticosteroids
  • Weak and brittle bones (osteoporosis)
  • Psoriasis
  • Underactive parathyroid (hypoparathyroidism)
  • Cavities
  • Hearth health
  • Immune system health
  • Respiratory health
  • Sexual reproductive health
  • Brain health and nervous system health

Certain individuals may not activate vitamin D to a usable state. These people may find themselves at risk of vitamin D deficiency and may need regular supplementation, including:
• older people
• people with darker skin
• people who are obese
• people with kidney or liver disease

References:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356951/#:~:text=Vitamin%20D%20is%20known%20to,muscle%20strength%2C%20thereby%20preventing%20falls.

https://pubmed.ncbi.nlm.nih.gov/15989379/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337085/

~Praveen Jada

*Do read the Disclaimer

Vitamin B12 Benefits, Foods Rich in Vitamin B12, Supplementation

  • All B vitamins are water-soluble. They help to convert carbohydrates, fats, and protein into energy, or glucose.
  • B vitamins are necessary for keeping the liver, skin, hair, and eyes healthy. They also play a role in the nervous system, and they are needed for good brain function.
  • The B vitamins are sometimes called anti-stress vitamins, because they boost the body’s immune system in times of stress.

Apart from D3, one another important vitamin that we need to focus on is B12 (Cobalamin). We find most of the people either deficient or not having optimum levels of B12. B12 levels can be determined from blood sample test.

Vitamin B-12 is needed for :

  • Nerve tissue health
  • Brain function
  • Production of red blood cells
  • Regulating DNA

Deficiency symptoms:

  • Nervous system and brain damage
  • Depression, confusion, memory problems, and fatigue
  • Constipation, loss of appetite, and weight loss
  • Numbness and tingling in the hands and feet
  • Anemia
  • In infants : growth problems, irritation, loss of appetite, loss of reflexes

Foods rich in B12:

Vitamin B-12 can be found naturally in animal products. It does not typically occur in plant foods.

  • Poultry/chicken
  • Lamb/mutton
  • Fish, especially haddock and tuna
  • Dairy products, such as milk, cheese, and yogurt
  • Whole Eggs (Yolk has B12)

Supplementation

People who do not eat meat, such as vegans, can obtain vitamin B-12 in supplement form. Methyl-cobalamin (Methyl group + B12) is the most active form of B12 and is be better absorbed and retained in our tissues than the synthetic cyanocobalamin. While buying supplements look out for Methyl-cobalamin B12.

Some researches suggest that B12 supplementation works in below cases

  • Vitamin B12 deficiency
  • High levels of homocysteine in the blood
  • An eye disease that leads to vision loss in older adults (age-related macular degeneration or AMD)
  • Nerve pain and Neuropathy
  • Cataracts
  • Memory and thinking skills
  • Strokes

References:

https://www.medicalnewstoday.com/articles/219822#deficiency-symptoms

https://www.healthline.com/nutrition/vitamin-b12-benefits#section1

https://www.webmd.com/vitamins/ai/ingredientmono-926/vitamin-b12

~Praveen Jada

*Do read the Disclaimer

Most Common Auto-Immune Diseases

A healthy immune system defends the body against disease and infection. But if the immune system malfunctions, it mistakenly attacks healthy cells, tissues, and organs. Called autoimmune disease, these attacks can affect any part of the body, weakening bodily function and even turning life-threatening.

Currently there is no clear scientific evidence why autoimmunity occurs however, medical community agrees that factors like Lifestyle, Diet, Environment, Hormones, Genetics and Epigenetics, Stress – all these play a crucial role in triggering auto-immunity.

Treatment for autoimmune diseases generally focuses on reducing immune system activity using lifestyle changes like diet, exercise, sleep, reducing stress or by using medications.

Most common Auto-immune diseases are:

References:

https://www.webmd.com/a-to-z-guides/autoimmune-diseases

https://www.healthline.com/health/autoimmune-disorders

~Praveen Jada

*Do read the Disclaimer

Main Inflammatory Markers to Focus in a Blood Test Report

Below are some of the important blood test markers for indicating inflammation in our body. These indicators signify the level of inflammation in our bodies. They could be used to analyze and treat various infections, chronic diseases, autoimmune diseases and and lifestyle disorders.

ANA (Antinuclear Antibody) Test 

Reference range: 1:40 to 1:60

An ANA test looks for antinuclear antibodies in your blood. If the test finds antinuclear antibodies in your blood, it may mean you have an autoimmune disorder. An autoimmune disorder causes your immune system to attack your own cells, tissues, and/or organs by mistake. These disorders can cause serious health problems.

Antibodies are proteins that your immune system makes to fight foreign substances like viruses and bacteria. But an antinuclear antibody attacks your own healthy cells instead. It’s called “antinuclear” because it targets the nucleus (center) of the cells.

HOMOCYSTEINE

Reference Range < 30

Homocysteine is linked to increased risk of premature coronary artery disease, stroke and thromboembolism. Moreover, Alzheimer’s disease, osteoporosis, venous thrombosis, schizophrenia, cognitive deficiency and pregnancy complications also elevates.

Elevated homocysteine levels might be due to increasing age, genetic traits, drugs, renal dysfunction and dietary deficiency of vitamins or smoking. To lower your homocysteine, eat more green vegetables, stop smoking, alcohol. Folic acid helps lowering elevated levels.

ANTI CCP or Anti-cyclic citrullinated peptide (ACCP)

Reference Range:

  • Negative : < 25
  • Positive : > 25

Anti-Cyclic-Citrullinated-Peptide (Anti-CCP) Antibodies hold promise for early and more accurate detection of Rheumatoid Arthritis before the disease proceeds into an irreversible damage. Anti-Cyclic-Citrullinated-Peptide (Anti-CCP) antibodies are detected using a solid phase enzyme immune assay having an analytical sensitivity of 25 RU/ml. Sensitivity of the method is 99% and specificity is 98.5%.

CYSTATIN C

Reference Range :-

  • <= 60 years: <= 1.03 mg/L
  • > 60 years : < 1.50 mg/L

Cystatin c, is a small 13-kda protein and is a member of the cysteine proteinase inhibitor family, it is produced at a constant rate by all nucleated cells. Due to its small size it is freely filtered by the glomerulus and is not secreted but is fully reabsorbed and broken down by the renal tubules. This means that the primary determinant of blood Cystatin c levels is the rate at which it is filtered at the glomerulus making it an excellent gfr marker. Cystatin c is also a marker of inflammation and like many other markers of inflammation; its serum concentration may be higher in patients with decreased renal clearance. There is mounting evidence, however, that Cystatin c may be a predictor of adverse outcomes independent of renal function with its higher sensitivity to detect a reduced GFR than Creatinine determination, also in the so-called “Creatinine-blind” range. Thus, Cystatin c is suggested to be a better marker for GFR than the ubiquitous serum Creatinine.

HIGH SENSITIVITY C-REACTIVE PROTEIN (HS-CRP)

Reference Range :-

Adult : <=3.0 mg/L

High sensitivity C-reactive protein, when used in conjunction with other clinical laboratory evaluation of acute coronary syndromes, may be useful as an independent marker of prognosis for recurrent events, in patients with stable coronary disease or acute coronary syndromes. hsCRP levels should not be substituted for assessment of traditional cardiovascular risk factors. Patients with persistently unexplained, marked evaluation of hsCRP after repeated testing should be evaluated for non – cardiovascular etiologies.

hsCRP measurements may be used as an independent risk marker for the identification of individuals at risk for future cardiovascular disease. Elevated CRP values may be indicative of prognosis of individuals with acute coronary syndromes, and may be useful in the management of such individuals.

Erythrocyte Sedimentation Rate

Reference range: The normal range is 0 to 22 mm/hr for men and 0 to 29 mm/hr for women.

ESR is an indirect measurement of plasma protein concentrations and is influenced by a number of disease states. Because the ESR depends on several proteins with varying half-lives, the rate rises and falls more slowly than do CRP concentrations. Furthermore, normal ESR values are specific to age and sex; the rate increases steadily with age and is higher in women than in men. Although CRP measurements have a clear advantage over ESR values the ESR test remains useful in the diagnosis of select conditions, particularly general bone lesions and osteomyelitis.

References:

https://medlineplus.gov/lab-tests/ana-antinuclear-antibody-test/

https://arupconsult.com/content/inflammatory-markers

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582449/

https://www.webmd.com/heart-disease/guide/homocysteine-risk#:~:text=Homocysteine%20is%20a%20common%20amino,as%20well%20as%20renal%20disease.

https://medlineplus.gov/lab-tests/homocysteine-test/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809312/

https://rheuminfo.com/common-tests/anti-ccp-antibody-anti-ccp/#:~:text=The%20anti%2DCCP%20(anti%2D,own%20tissues%20are%20made%20of.

https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=cystatin_c

https://www.medicinenet.com/script/main/art.asp?articlekey=39781

https://www.webmd.com/a-to-z-guides/c-reactive-protein-test

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669860/

~Praveen Jada

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Anti-Inflammatory Diet

An Anti-Inflammatory diet is a diet that does not induce immune response in our bodies which causes inflammation. It nurtures and strengthens the immune system instead of triggering it needlessly.

Read Chronic Inflammation, Causes, Risks – Fit Body to Fit Mind

Read Acute vs Chronic diseases – Fit Body to Fit Mind

In simple terms we can call a diet as anti-inflammatory if it serves our body’s best interests and vitalize our body inside-out.

There is no particular diet to name as anti-inflammatory. A type of food which is anti-inflammatory for people in one part of the geography might be inflammatory to a different set of people living in a different location. So, it is important to note that we need to eat a diet that is aligned with our ancestral origins, that our body accepts, that nourishes us, that heals us, that rejuvenates us, that repairs and grows our tissue, that helps us age gracefully.

There are certain common fundamentals that we need to follow when are are designing a diet that serves us well. The diet should include foods rich in antioxidants, bioflavonoids, polyphenols, phytonutrients, fiber, healthy fats, quality protein, complex carbohydrates.

  • A lots of seasonal vegetables and fruits
  • Foods rich in quality protein
  • Foods rich in Omega 3 fatty acids
  • Healthy fats – cold pressed or unrefined oils for cooking.
  • Complex carbohydrates
  • Spices and herbs

What needs to be avoided: Inflammatory foods and habits

Nevertheless, there are some exceptional cases where some of us may have issues with some food groups even though they are nutritious in general. Reason is every person’s body may respond differently to a given food. To know more about this, refer Elimination Diet

~Praveen Jada

*Do read the Disclaimer

Chronic Inflammation, Causes, Risks

Chronic inflammation can have long-term and whole-body effects. Chronic inflammation is also called persistent, low-grade inflammation because it produces a steady, low-level of inflammation throughout the body, as judged by a small rise in immune system markers found in blood or tissue.

Low levels of inflammation can be triggered by a perceived internal threat, even when there isn’t a disease to fight or an injury to heal, and sometimes this signals the immune system to respond. As a result, white blood cells swarm but have nothing to do and nowhere to go, and they may eventually start attacking internal organs or other healthy tissues and cells.

For example, chronic inflammation has been linked to heart disease and stroke according to American Heart Association. Cancer is another disease linked with chronic inflammation. Over time, chronic inflammation can cause DNA damage and lead to some forms of cancer, according to the National Cancer Institute. Anything that causes inflammation will cause the DNA of a cell to replicate faster. The more your cells replicate, the higher chance you have of cancers developing.

Chronic, low-grade inflammation often does not have symptoms but one can test for various inflammatory markers in blood test. Besides looking for clues in the blood, a person’s diet, lifestyle habits and environmental exposures can contribute to chronic inflammation.

It’s important to maintain a healthy lifestyle to keep inflammation in check, more importantly following an anti-inflammatory diet.

Causes of chronic inflammation:

The reason inflammation becomes chronic isn’t always apparent. It may be caused by

  • Lack of exercise and proper diet
  • Lack of sleep and experiencing a lot stress
  • infections that don’t go away
  • eating a lot of sugary foods, fried foods, baked foods
  • eating processed and packaged foods with added preservatives, artificial colors and flavors
  • certain conditions like obesity, high blood sugar, high blood pressure
  • habits like smoking and drinking alcohol,
  • environmental exposure to pollutants and toxins

Chronic inflammation could lead a lot of health complications such as

  • Metabolic syndrome.
  • Type 2 diabetes.
  • Cardiovascular disease.
  • Nonalcoholic fatty liver disease.
  • Hypertension.
  • Chronic kidney disease.
  • Depression.
  • Various types of cancer.
  • Neurodegenerative and autoimmune diseases.
  • Osteoporosis. Sarcopenia

References:

https://www.cancercenter.com/community/blog/2018/08/inflammation-linked-to-cancer-but-lifestyle-changes-may-help

Chronic inflammation needs focused research to reduce disease

https://www.livescience.com/52344-inflammation.html

https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072482/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492709

~Praveen Jada

*Do read the Disclaimer

Foods and Supplements for Improving Thyroid Function

Foods good for proper thyroid function

  • Eggs: whole eggs are best, as much of their iodine and selenium are found in the yolk, while the whites are full of protein
  • Meat: all meats, including lamb, beef, chicken, etc.
  • Fish: all seafood, including salmon, tuna, halibut, shrimp, etc.
  • Vegetables: Eat a lot of colorful vegetables (cruciferous vegetables like cauliflower, cabbage, broccoli, Brussels sprouts are fine to eat in moderate amounts as they affect Thyroid function negatively)
  • Gluten-free grains and seeds: rice, oats, pumpkin seeds, buckwheat, quinoa, chia seeds, flax seed, millets
  • Nuts and seeds: Almonds, Cashews, Walnuts, Peanuts, Walnuts, Flaxseeds.
  • Lentils, Beans and Pulses.
  • Healthy Fats: Ghee, Butter, Coconut Oil, Olive Oil, Mustard Oil and other unrefined oils.
  • Fruits: All fruits are good. Try to include different variety of colorful fruits.

Supplements that could support Thyroid function and to improve hypothyroidism:

  • Vitamin A
  • Vitamin D3
  • Vitamin B12
  • Vitamin C
  • Zinc
  • Selenium
  • Myo-Inositol
  • Iodine
  • Iron
  • Magnesium
  • Kelp extract
  • Curcumin
  • Omega 3 Fatty Acids (EPA and DHA)
  • L-Carnitine
  • L-Tyrosine – Not enough researches to prove that Tyrosine could improve Thyroid function. However, it could indirectly impact Thyroid functions as it said to increase levels of the neurotransmitters dopamine, adrenaline and norepinephrine which increase body’s metabolism and in turn could improve Thyroid function. Good sources of tyrosine are meats, dairy, and legumes.
  • According to some researches vitamin D, selenium, L-carnitine, and vitamin B12 may help people with Graves’ disease (Auto-immune Hyperthyroidism).
  • Some animal and test-tube research suggests that omega-3 fats, curcumin, L-carnitine, quercetin, melatonin, resveratrol, selenium, inositol, zinc, and vitamins C, E, A, and D may benefit those with thyroid cancer.

Iodine Rich Foods

Iodine is particularly important when it comes to Thyroid health and optimum functioning. Iodine is critical for your thyroid and plays an important role in the production of thyroid hormone. If you aren’t getting enough iodine, you may start to develop symptoms of hypothyroidism.

  • Seaweed
  • Kelp
  • Iodized salt
  • Milk and Dairy Products like yogurt, curd
  • Prunes
  • Lima Beans
  • Cod fish
  • Tuna
  • Eggs
  • Liver
  • Iodine enriched foods

Foods to Avoid

  • Soy, Tofu
  • Cruciferous Vegetables Like Broccoli and Cauliflower
  • Gluten – Whole wheat, barley, rye
  • Deep fried foods
  • Sugary foods – chocolates, cookies, cakes, candies etc.,
  • Ultra processed foods and packaged foods
  • Drinking alcohol and smoking
  • Refined foods and refined oils. Do not reuse oil.

References and Interesting reads below:

Treating Hypothyroidism: Can Vitamins and Supplements Help?

About Thyroid Vitamins

Tyrosine: Benefits

https://www.karger.com/Article/FullText/505094

https://www.healthline.com/health/hyperthyroidism-diet#foods-to-avoid

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770945/

https://pubmed.ncbi.nlm.nih.gov/28290237/

https://www.webmd.com/diet/foods-high-in-iodine#1

~Praveen Jada

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