If you cannot change certain people or certain conditions in life, then
ignore them or distance yourself from them if possible. If not then have radical acceptance of the current circumstances in life.
If you have the possibility to change things, then
Muster up the courage to take action and enable change.
Now comes the important part,
You need to develop the wisdom to decide between what to change and what to accept. Wisdom comes from experiences. Everyone experiences life, but very few observe the experience of life and derive meaning out of experience. Consciousness is the time between the stimulus and our reaction to it. Our mind runs through different thoughts during the state of consciousness. The more time we spend in conscious state, the better our thoughts become. This enables us to learn from the experiences rather than being casual about various things in life. You improve your wisdom through practical application of your learning and keep improving.
*Do read the Disclaimer